Icon of the Instituts for Quality and Efficiency in Health Care

[A17-46] Pembrolizumab (urothelial carcinoma) - Benefit assessment according to §35a Social Code Book V

Last updated 04.01.2018

Project no.:
A17-46

Commission:
Commission awarded on 13.09.2017 by the Federal Joint Committee (G-BA).

Report type:
Dossier assessment

Status:
Commission completed

Department/Division:
Drug Assessment

Topic:
Cancer

Indication:

Adult patients with locally advanced or metastatic urothelial cell carcinoma

Result of dossier assessment:

First-line, cisplatin-based therapy unsuitable: added benefit not proven. After pretreatment with platinum-based chemotherapy: indication of considerable added benefit.

Note:

After completion of the assessment by IQWiG the Federal Joint Committee (G-BA) conducts a commenting procedure. This may provide supplementary information and as a result lead to a modified benefit assessment. Further information and the decision on the early benefit assessment can be found on the relevant page of the G-BA website.

informedhealth.org logo Accompanying information

Further information for consumers and patients is provided on IQWiG's health information website www.informedhealth.org.
Pembrolizumab (Keytruda) for the treatment of advanced bladder cancer (urothelial carcinoma)

Project no. Title Status
A19-99 Pembrolizumab (combination with axitinib, renal cell carcinoma) - Benefit assessment according to §35a Social Code Book V Commission completed
A19-31 Pembrolizumab (squamous non-small cell lung cancer) - Benefit assessment according to §35a Social Code Book V Commission completed
A19-30 Pembrolizumab (non-squamous non-small cell lung cancer) - Benefit assessment according to §35a Social Code Book V Commission completed
A19-29 Pembrolizumab (melanoma) - Benefit assessment according to §35a Social Code Book V Commission completed
A19-101 Pembrolizumab (head and neck squamous cell carcinoma, combination therapy) - Benefit assessment according to §35a Social Code Book V Commission completed
A19-100 Pembrolizumab (head and neck squamous cell carcinoma, monotherapy) - Benefit assessment according to §35a Social Code Book V Commission completed
A18-89 Pembrolizumab (urothelial carcinoma, first line) - Benefit assessment according to §35a Social Code Book V (new scientific findings) Commission completed
A18-67 Pembrolizumab (head and neck squamous cell carcinoma) - Benefit assessment according to §35a Social Code Book V Commission completed
A17-23 Pembrolizumab (classical Hodgkin lymphoma) - Benefit assessment according to §35a Social Code Book V Commission completed
A17-06 Pembrolizumab (non-small cell lung cancer) - Benefit assessment according to §35a Social Code Book V Commission completed
A16-55 Pembrolizumab (non-small cell lung cancer) - Benefit assessment according to §35a Social Code Book V Commission completed
A15-33 Pembrolizumab - Benefit assessment according to §35a Social Code Book V (dossier assessment) Commission completed
A24-104 Pembrolizumab (TNBC, neoadjuvant and adjuvant) – Benefit assessment according to §35a Social Code Book V (expiry of the decision) Commission work started
A24-99 Pembrolizumab (urothelial cancer, first line) – Benefit assessment according to §35a Social Code Book V Commission work started
A24-46 Pembrolizumab (NSCLC, neoadjuvant + adjuvant) – Benefit assessment according to § 35a Social Code Book V Commission completed
A24-03 Pembrolizumab (biliary cancer) – Benefit assessment according to §35a Social Code Book V Commission completed
A24-47 Pembrolizumab (NSCLC, adjuvant) – Benefit assessment according to § 35a Social Code Book V Commission completed
A24-02 Pembrolizumab (gastric cancer, HER2-negative) – Benefit assessment according to §35a Social Code Book V Commission completed
A24-01 Pembrolizumab (gastric or gastro-oesophageal junction adenocarcinoma, HER2-positive) – Benefit assessment according to §35a Social Code Book V Commission completed
A22-70 Pembrolizumab (cervical cancer) – Benefit assessment according to § 35a SGB V Commission completed
A22-71 Pembrolizumab (renal cell carcinoma) – Benefit assessment according to § 35a SGB V Commission completed
A22-79 Pembrolizumab (bile cancer) – Benefit assessment according to § 35a SGB V Commission completed
A22-78 Pembrolizumab (small bowel cancer) – Benefit assessment according to §35a Social Code Book V Commission completed
A22-77 Pembrolizumab (gastric cancer) – Benefit assessment according to §35a Social Code Book V Commission completed
A22-76 Pembrolizumab (endometrial cancer) – Benefit assessment according to §35a Social Code Book V Commission completed
A22-75 Pembrolizumab (colorectal cancer) – Benefit assessment according to § 35a SGB V Commission completed
A21-163 Pembrolizumab (renal cell carcinoma) - Benefit assessment according to §35a Social Code Book V Commission completed
A21-164 Pembrolizumab (endometrial carcinoma) - Benefit assessment according to §35a Social Code Book V Commission completed
A22-73 Pembrolizumab (melanoma, advanced) – Benefit assessment according to § 35a SGB V Commission completed
A22-72 Pembrolizumab (melanoma, adjuvant) – Benefit assessment according to § 35a SGB V Commission completed
A21-144 Pembrolizumab (oesophageal cancer) - Benefit assessment according to §35a Social Code Book V Commission completed
A21-145 Pembrolizumab (breast cancer, triple-negative, locally recurrent/metastatic, in combination with chemotherapy) - Benefit assessment according to §35a Social Code Book V Commission completed
A22-63 Pembrolizumab (breast cancer) - Benefit assessment according to § 35a Social Code Book V Commission completed
A21-34 Pembrolizumab (urothelial carcinoma first line treatment) - Benefit assessment according to §35a Social Code Book V (expiry of the decision) Commission completed
A21-35 Pembrolizumab (Hodgkin lymphoma) - Benefit assessment according to §35a Social Code Book V Commission completed
A21-36 Pembrolizumab (colorectal cancer) - Benefit assessment according to §35a Social Code Book V Commission completed

Federal Joint Committee (G-BA)

2018-08-02 A G-BA decision was published.

G-BA documents on this decision

Contact

Press contact

+49 221 356850

presse@iqwig.de

Info Service (German)

Subscribe to daily updated information on projects, calls for tender, current vacancies and events as well as our press releases.

Register

Contact form

Questions about commissions, publications and press releases can be sent to us via this form.

Contact form

Print page