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[A17-46] Pembrolizumab (urothelial carcinoma) - Benefit assessment according to §35a Social Code Book V

Last updated 04.01.2018

Project no.:
A17-46

Commission:
Commission awarded on 13.09.2017 by the Federal Joint Committee (G-BA).

Report type:
Dossier assessment

Status:
Commission completed

Department/Division:
Drug Assessment

Application field:
Cancer

Indication:

Adult patients with locally advanced or metastatic urothelial cell carcinoma

Result of dossier assessment:

First-line, cisplatin-based therapy unsuitable: added benefit not proven. After pretreatment with platinum-based chemotherapy: indication of considerable added benefit.

Note:

After completion of the assessment by IQWiG the Federal Joint Committee (G-BA) conducts a commenting procedure. This may provide supplementary information and as a result lead to a modified benefit assessment. Further information and the decision on the early benefit assessment can be found on the relevant page of the G-BA website.

informedhealth.org logo Accompanying information

Further information for consumers and patients is provided on IQWiG's health information website www.informedhealth.org.
Pembrolizumab (Keytruda) for the treatment of advanced bladder cancer (urothelial carcinoma)

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A22-77 Pembrolizumab (gastric cancer) – Benefit assessment according to §35a Social Code Book V Commission completed
A22-76 Pembrolizumab (endometrial cancer) – Benefit assessment according to §35a Social Code Book V Commission completed
A22-75 Pembrolizumab (colorectal cancer) – Benefit assessment according to § 35a SGB V Commission completed
A21-163 Pembrolizumab (renal cell carcinoma) - Benefit assessment according to §35a Social Code Book V Commission completed
A21-164 Pembrolizumab (endometrial carcinoma) - Benefit assessment according to §35a Social Code Book V Commission completed
A22-73 Pembrolizumab (melanoma, advanced) – Benefit assessment according to § 35a SGB V Commission completed
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A21-144 Pembrolizumab (oesophageal cancer) - Benefit assessment according to §35a Social Code Book V Commission completed
A21-145 Pembrolizumab (breast cancer, triple-negative, locally recurrent/metastatic, in combination with chemotherapy) - Benefit assessment according to §35a Social Code Book V Commission completed
A22-63 Pembrolizumab (breast cancer) - Benefit assessment according to § 35a Social Code Book V Commission completed
A21-34 Pembrolizumab (urothelial carcinoma first line treatment) - Benefit assessment according to §35a Social Code Book V (expiry of the decision) Commission completed
A21-35 Pembrolizumab (Hodgkin lymphoma) - Benefit assessment according to §35a Social Code Book V Commission completed
A21-36 Pembrolizumab (colorectal cancer) - Benefit assessment according to §35a Social Code Book V Commission completed

Federal Joint Committee (G-BA)

2018-08-02 A G-BA decision was published.

G-BA documents on this decision

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