[A20-111] Olaparib (ovarian cancer; first-line maintenance in combination with bevacizumab) - Benefit assessment according to §35a Social Code Book V

Last updated 04.06.2021

Project no.:
A20-111

Commission:
Commission awarded on 02.12.2020 by the Federal Joint Committee (G-BA).

Report type:
Dossier assessment

Status:
Commission completed

Department/Division:
Drug Assessment

Topic:
Cancer

Indication:

Adult patients with advanced (FIGO stages III and V) high-grade epithelial ovarian, fallopian tube or primary peritoneal cancer who are in response (complete or partial) following completion of first-line platinum-based chemotherapy in combination with bevacizumab and whose cancer is associated with homologous recombination deficiency (HRD) positive status.

Result of dossier assessment:

Patients without detectable tumour after primary surgery and patients without detectable tumour/with complete response following chemotherapy: indication of considerable added benefit.

Patients without detectable tumour after interval surgery and patients with partial response: indication of lesser benefit.

Note:

After completion of the assessment by IQWiG the Federal Joint Committee (G-BA) conducts a commenting procedure. This may provide supplementary information and as a result lead to a modified benefit assessment. Further information and the decision on the early benefit assessment can be found on the relevant page of the G-BA website.

Project no. Title Status
A19-56 Olaparib (ovarian cancer) - Benefit assessment according to §35a Social Code Book V Commission completed
A19-57 Olaparib (breast cancer) - Benefit assessment according to §35a Social Code Book V Commission completed
A18-36 Olaparib (ovarian, fallopian tube, peritoneal cancer) - Benefit assessment according to §35a Social Code Book V Commission completed
G15-05 Olaparib - Assessment according to §35a (para. 1., sentence 10) Social Code Book V (dossier assessment) Commission completed
A20-115 Olaparib (adenocarcinoma of the pancreas) - Benefit assessment according to §35a Social Code Book V Commission completed
A20-106 Olaparib (prostate cancer) - Benefit assessment according to §35a Social Code Book V Commission completed
A21-55 Olaparib (ovarian cancer; first-line maintenance in combination with bevacizumab) - Addendum to Commission A20-111 Commission completed
A22-117 Olaparib (ovarian cancer) - Benefit assessment according to §35a Social Code Book V Commission completed
A23-03 Olaparib (prostate cancer) - Benefit assessment according to § 35a SGB V Commission completed
A24-88 Olaparib (maintenance in combination with durvalumab; endometrial cancer) – Benefit assessment according to §35a Social Code Book V Commission completed
A23-32 Olaparib (ovarian cancer) – Benefit assessment according to §35a Social Code Book V Commission completed
A22-89 Olaparib (breast cancer, adjuvant) – Benefit assessment according to §35a Social Code Book V Commission completed

Federal Joint Committee (G-BA)

2021.06.04 A G-BA decision was published.

G-BA documents on this decision

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