[A21-115] Tofacitinib (rheumatoid arthritis) - Benefit assessment according to §35a Social Code Book V (new scientific findings)

Last updated 17.02.2022

Project no.:
A21-115

Commission:
Commission awarded on 31.08.2021 by the Federal Joint Committee (G-BA).

Report type:
Dossier assessment

Status:
Commission completed

Department/Division:
Drug Assessment

Topic:
Muscles, bones and joints

Indication:

Adults with moderate to severe active rheumatoid arthritis

Result of dossier assessment:
  • Patients without poor prognostic factors who have responded inadequately to or who have not tolerated prior treatment with a disease-modifying antirheumatic drug (conventional synthetic DMARDs, including methotrexate): added benefit not proven
  • Patients for whom a first therapy with biologic DMARDs or targeted synthetic DMARDs is indicated: added benefit not proven
  • Patients who have responded inadequately to or who have not tolerated prior treatment with one or more biologic DMARDs and/or targeted synthetic DMARDs: added benefit not proven
Note:

After completion of the assessment by IQWiG the Federal Joint Committee (G-BA) conducts a commenting procedure. This may provide supplementary information and as a result lead to a modified benefit assessment. Further information and the decision on the early benefit assessment can be found on the relevant page of the G-BA website.

informedhealth.org logo Accompanying information

Further information for consumers and patients is provided on IQWiG's health information website www.informedhealth.org.

Federal Joint Committee (G-BA)

2022-02-17 A G-BA decision was published.

G-BA documents on this decision

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