[A22-65] Selpercatinib (advanced NSCLC with RET fusion) – Benefit assessment according to § 35a SGB V
Last updated 04.10.2022
Project no.:
A22-65
Commission:
Commission awarded on 30.06.2022 by the Federal Joint Committee (G-BA).
Report type:
Dossier assessment
Status:
Commission completed
Department/Division:
Drug Assessment
Application field:
Cancer
Indication:
Adults with advanced RET fusion-positive non-small cell lung cancer; first-line therapy
Result of dossier assessment:
- Patients with PD-L1 expression ≥ 50% of tumour cells: added benefit not proven
- Patients with PD-L1 expression < 50% of tumour cells: added benefit not proven
Note:
After completion of the assessment by IQWiG the Federal Joint Committee (G-BA) conducts a commenting procedure. This may provide supplementary information and as a result lead to a modified benefit assessment. Further information and the decision on the early benefit assessment can be found on the relevant page of the G-BA website.
| Project no. | Title | Status |
|---|---|---|
| A21-29 | Selpercatinib (RET fusion-positive thyroid cancer) - Benefit assessment according to §35a Social Code Book V | Commission completed |
| A21-28 | Selpercatinib (RET mutant medullary thyroid cancer) - Benefit assessment according to §35a Social Code Book V | Commission completed |
| A21-27 | Selpercatinib (non-small cell lung cancer) - Benefit assessment according to §35a Social Code Book V | Commission completed |
| A24-62 | Selpercatinib (thyroid cancer) - Benefit assessment according to § 35a Social Code Book V | Commission completed |
| A24-63 | Selpercatinib (solid tumours) - Benefit assessment according to § 35a Social Code Book V | Commission completed |
| A22-106 | Selpercatinib (thyroid cancer) – Benefit assessment according to §35a Social Code Book V | Commission completed |