[A24-86] Durvalumab (first-line in combination with carboplatin and paclitaxel, maintenance in combination with olaparib; endometrial cancer) – Benefit assessment according to §35a Social Code Book V

Last updated 02.12.2024

Project no.:
A24-86

Commission:
Commission awarded on 22.08.2024 by the Federal Joint Committee (G-BA).

Report type:
Dossier assessment

Status:
Commission completed

Department/Division:
Drug Assessment

Topic:
Cancer

Indication:

First-line treatment of adult patients with primary advanced or recurrent mismatch repair proficient endometrial cancer who are candidates for systemic therapy, followed by maintenance treatment with durvalumab in combination with olaparib

Result of dossier assessment:
  • Patients with newly diagnosed disease: hint of considerable added benefit
  • Patients with recurrent disease: hint of lesser benefit
Note:

After completion of the assessment by IQWiG the Federal Joint Committee (G-BA) conducts a commenting procedure. This may provide supplementary information and as a result lead to a modified benefit assessment. Further information and the decision on the early benefit assessment can be found on the relevant page of the G-BA website.

DOI:

https://doi.org/10.60584/A24-86

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